Dr. Michael Hadjigavriel

Dr. Michael Hadjigavriel

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Dr. Michael Hadjigavriel

 


Dr. Michael Hadjigavriel MD, PhD

Nephrology / Transplant Nephrology 


 

 

Personal Information

Personal Information

Languages:
English, Italian, Greek
Fax:
22516171

Location Information

Postal Address:
A. Michalakopoulou 25, Apt 201
Town/Village:
Nicosia
Postal Code:
1075
City Name:
Nicosia

Education

University:
University of Bologna, Italy
Other Universities:
University of Helsinki, Finland
Associations:
ASSOCIATE MEMBER OF MOLECULAR MEDICINE RESEARCH CENTER UNIVERSITY OF CYPRUS, NATIONAL DELEGATE AT THE EUROPEAN COUNCIL FOR THE EUROPEAN COMMITTEE ON ORGAN TRANSPLANTATION (EDQM) 2014-2017, MEMBER OF THE ADVISORY BOARD OF THE MEDICAL SCHOOL OF THE EUROPEAN UNIVERSITY CYPRUS (EUC), MEMBER OF THE BOARD OF DIRECTORS OF THE CYPRUS INSTITUTE OF NEUROLOGY AND GENETICS (CING)

Awards - Qualifications

Certifications:

UNIVERSITY
  • University of Bologna, Italy - Faculty of Medicine and Surgery. THESIS: The secretory activity of biliary acids in the colon. Degree: “Dottore in Medicina e Chirurgia”. (English trans: Doctor in Medicine and Surgery) 
  • Italian State Examination for Professional Ability 

POST-GRADUATE STUDIES
  • Nephrology School, Sant’ Orsola University Hospital, Bologna, Italy (Italian Government Scholarship from the Ministry of Foreign Affairs). DEGREE: “Dottore in Medicina e Chirurgia Specialista in Nefrologia”. (English trans : Doctor in Medicine and Surgery Specialized in Nephrology) 
  • PhD (THESIS): The clinical and morphological aspects of chronic hereditary nephritis.Tutor: Prof.  V. Bonomini, Director Institute of   Nephrology , School of Medicine, University of Bologna 

POST-GRADUATE COURSES
  • Transplantation Laboratory, University of Helsinki, Finland: Renal Biopsy and fine needle aspiration biopsy in renal transplantation
  • Department of Ultrasonography, Rambam Hospital, Haifa, Israel: Invasive Ultrasonography and Ultrasonographic assessment of Transplant kidney

Background

Practice Experience:
(1986-2008)
Transplant Nephrologist
Paraskevaidion Transplant Centre
 
(2008-2017)
Director Nephrology and Dialysis
Larnaca General Hospital                     
 
(2013-CURRENT)
Associate Member
Molecular Medicine Research Centre
University of Cyprus
                   
(2014-2017)
National Delegate
European Committee for Organ transplantation (EDQM)
Council of Europe
 
(2016-CURRENT)
Scientific Collaborator / Professor of Nephrology
European University Cyprus (EUC)
 
(2017-CURRENT)
Member Advisory Board
School of Medicine
European University Cyprus (EUC)           
 
(2017-CURRENT)
Member Board of Directors
Institute of Neurology and Genetics (CING) 

Doctor Specialties

NEPHROLOGIST
Special Expertise:
Transplant Medicine
Immunosuppression

Other Info

Special Services & Expertise:
Central Catheter insertion for Haemodialysis
Renal Biopsy
Publications & Presentations:
PUBLICATIONS & PRESENTATIONS
1. Pathogenesis and prevention of osteonecrosis after renal transplantation. C. Feletti, A. Di Felice, M. Biavati, M. Hadjigavriel, V. Bonomini. Sant; Orsola University Hospital, Bologna, Italy. Mineral Metabolism Research in Italy, Wichting Editor, Milan, Vol 4, 1983. 

2. La Radioterapia locale nella crisi  di rigetto acuto dei trapiantati renali. V. Brandoli*, M. Hadjigavriel, A. Vangelista, V. Pasquinelli*. Institute of nephrology and *Institute of Radiotherapy ” L.Galvani”, S. orsola university Hopsital, Bologna, Italy. Clueb Editor Bologna, 1983. 

3. La Emoperfusione nel trattamento dei sintomi uremici resistenti alla terapia dialytica convenzionale. Feliciangeli G., Stefoni S., Coli L., Hadjigavriel M., Baldrati L., Cucudis P., Biavati M., Institute of Nephrolofy, S. Orsola university Hospital, Bologna, Italy,  University of Abbruzzo Editions, 1983. 

4. Evaluation of metabolic response induced by a maximal exercise in different sport practice. I. Alberazzi, A. Bargossi*, W. Randi*, A. Frascari*, M. Hadjigavriel.Institute of Nephrology and *Central laboratory, S. Orsola University Hospital, Bologna, Italy. International Journal of Sports Medicine, Thieme Stratton Inc., New York, Sept. 1983. 

5. Lipid and Apolipoprotein serum concentrations in the hyperlipaedemia of nephrotic syndrome. G. Orsoni, C. Raimondi, G. Liviano D; Arcangelo, M. Hadjigavriel, A. Vangelista, AQ.M. Bargossi*, O. Cappelletti*, P. Masotti*, V. Bonomini. Institute of Nephrology and *Central laboratory, S. Orsola University Hospital, Bologna. In Book: Atherosclerosdis and Cardiovascular Diseases, S. Lenzi and G.C. Descovich Eds., Editrice Compositori , Bologna, Italy, 1984 pages:179-184. 
6. Effects of different training techniques on lipid pattern in athletes and comparison to a matched group of blood donors. M. Hadjigavriel, I. Albertazzi, A.M. Bargossi*, O. Cappelletti*, A. Dormi*, W. Randi*. Institute of Nephrology and Dialysis, * Institute of Clinica medica general e Terapia Medica II, S. Orsola University Hospital, Bologtna, Italy. In Book: Atherosclorosis and Cardiovascular Diseases S./ Lenzi and G.C. Descovic eds., Editrice Compopsitori, Bologna, Italy, 1984,  pages 143-148. 

7. Distribuzione del fattore lipoproteico Lp(a) in un gruppo di donator di sangue. M. Hadjigavriel, I. Albertazzi, A.M. Bargossi*, O. Cappelletti*, A. Dormi*, W. Randi*. Institute of Nephrology and Dialysis, * Institute of Clinica medica general e Terapia Medica II, S. Orsola University Hospital, Bologtna, Italy. In Book: Atherosclorosis and Cardiovascular Diseases S./ Lenzi and G.C. Descovic eds., Editrice Compopsitori, Bologna, Italy, 1984.  

8. Effetti della radioterapia nella crisi di rigetto acuto dei trapiantati renali V. Brandoli*, M. Hadjigavriel, A. Vangelista, V. Pasquinelli*. Institute of nephrology and *Institute of Radiotherapy ” L.Galvani”, S. orsola university Hopsital, Bologna, Italy. Clueb Editor Bologna, 1984. 

9. Escrezione urinaria di callicreina nell’ ipertensione arteriosa dopo trapianto renale.C.Campieri, M. Hadjigavriel, R.Mignani, B.Stagni, A. Vangelista, V.Bonomini .Institute of Nephrology, S. Orsola University Hospital, Bologna, Italy, ACTA MEDICA Editions s.r.l., Rome, 1985. 

10. Reduced Serum concentrations of total and free Iodothyronines in chronic renal failure.G.Orsoni, M.Hadjigavriel, F. Fatone, A.Vangelista, V.Bonomini. Institute of Nephrology., S. Orsola university Hospital, Bologna, Italy, Bari Nephrology Editions, 1985.    

11. Short-term, high-dose muzolimine treatment in patients with chronic renal failure and acute fluid retention. Orsoni G, Di Felice A, Hadjigavriel M, Biavati M, Bonomini V.Institute of Nephrology and Dialysis, Sant’ Orsola University Hospital, Bologna, Italy. Z Kardiol. 1985; 74 Suppl 2:121-4. 

12. Προοπτικές στα τεχνγητά όργανα. Μ. Χατζηγαβνριήλ. Cyprus medical Iournal Vol. D’ No.3, Third period, 1985, pages 15-19.        

13. Renal transplantation in a developing country (Cyprus). Kyriakides GK, Hadjigavriel M, Pierides A, Chouris S, Kyriakides M, Varnavides A. Surgical and Transplant Foundation, Nicosia, Cyprus. Transplant Proc. 1989 Feb; 21(1 Pt 2):2182-3. 

14. Renal transplantation in Cyprus. Kyriakides GK, Hadjigavriel M, Hadjicostas P, Nicolaides A, Kyriakides M. Paraskevaidion Surgical and Transplant Center, Nicosia, Cyprus. Transplant Proc. 1993 Jun; 25(3):2361 

15. Public awareness and attitudes toward transplantation in Cyprus. Kyriakides G, Hadjigavriel M, Hadjicostas P, Nicolaides A, Kyriakides M. Paraskevaidion Surgical and Transplant Foundation, Nicosia, Cyprus. Transplant Proc. 1993 Jun;25 (3):2279 

16. Pediatric renal transplants in Cyprus. Kyriakides GK, Hadjigavriel M, Nicolaidou A, Nicolaou P. Paraskevaidion Surgical and Transplant Center, Nicosia, Cyprus. Transplant Proc. 1997 Nov; 29 (7):3077 

17. Fluvastatin in renal transplantation. Hadjigavriel M, Kyriakides G.Paraskevaidion Surgical and Transplant Center, Nicosia, Cyprus. Transplant Proc. 1997 Nov; 29 (7):3050. 

18. Loss of the polycystic kidney disease (PKD1) region of chromosome 16p13 in renal cyst cells supports a loss-of-function model for cyst pathogenesis. Koptides M, Constantinides R, Kyriakides G,Hadjigavriel M, Patsalis PC .J Clin Invest 99: 194-199. Genes Chromosomes Cancer 49: 669-681. Brasier JL, Henske EP 
 
19. Loss of heterozygosity in polycystic kidney disease with a missense mutation in the repeated region of PKD1.Koptides M, Constantinides R, Kyriakides G, Hadjigavriel M, Patsalis PC, Pierides A, Deltas CC. The Cyprus Institute of Neurology and Genetics, Department of Molecular Genetics, Nicosia. Hum Genet. 1998 Dec; 103 (6):709-17. 

20. Efficacy and safety of losartan in renal transplant recipients. Hadjigavriel M, Kyriakides G. Paraskevaidion Surgical and Transplant Center, Nicosia, Cyprus. Transplant Proc. 1999 Dec; 31 (8):3300-1. 

21. Genetic evidence for cooperative interaction of polycystins 1 and 2, which are mutated in polycystic kidney disease (ADPKD). Deltas C, Mean R, Kyriakides G, Hadjigavriel M, Demetriou K, Pierides A, Koptides M. The Cyprus Institute of Neurology and Genetics, Department of Molecular Genetics, Nicosia. Am J Hum Genet 1999;66 (suppl):A108-A571. 

22. Renal transplantation in Cyprus. Kyriakides G, Pouloukas S, Hadjigavriel M, Nicolaou P, Alaiddine M, Kyriakides M, Nicolaidou AV. Paraskevaidion Surgical and Transplant Center, Nicosia, Cyprus. Clin Transpl. 2000:355-6 

23. Living unrelated renal transplants in Cyprus. Kyriakides G, Pouloukas S, Hadjigavriel M, Nicolaidou A. Paraskevaidion Surgical and Transplant Center, Nicosia, Cyprus. Transplant Proc. 2002 Dec; 34(8):3104-5. 
 
24. X-linked Alport syndrome in Hellenic families: phenotypic heterogeneity and mutations near interruptions of the collagen domain in COL4A5  P Demosthenous, K Voskarides, K Stylianou, M Hadjigavriel, M Arsali, C Patsias, E Georgaki, P Zirogiannis, C Stavrou, E Daphnis, A Pierides, C   Deltas Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus. Clinical Genetics  02/2011; 81(3):240-8. DOI:10.1111/j.1399-0004.2011.01647. 

25. The Many Faces of Thin Basement Membrane Nephropathy; A Population Based Study Kyriacos Kyriacou, Marianna Nearchou, Ioanna Zouvani, Christina Flouri, Maria Loizidou, Michael Hadjigavriel, Andreas Hadjisavvas, Kyriacos Ioannou  04/2012; ISBN: 978-953-51-0477-3 In book: Topics in Renal Biopsy and Pathology 

26. X-linked, COL4A5 hypomorphic Alport mutations such as G624D and P628L may only exhibit thin basement membrane nephropathy with microhematuria and late onset kidney failure  A Pierides, K Voskarides, M Kkolou, M Hadjigavriel, C Deltas      Hippokratia  01/2013; 17(3):207-213. 

27. Frequency of COL4A3/Col4A4 mutations amongst families segregating glomerular microscopic hematuria and evidence for activation of the unfolded protein response   Louiza Papazachariou; Panayiota Demosthenous; Myrtani Pieri; Gregory Papagregoriou; Isavella Savva; Christoforos Stavrou; Michael Zavros; Yiannis Athanasiou; Kyriakos Ioannou; Charalambos Patsias; Alexia Panagides; Costas Potamitis; Kyproula Demetriou; Michael Hadjigavriel; Maria Kkolou; Panayiota Loukaidou; Androulla Pastelli; Aristos Michael; Maria Arsali; Loukas Damianou; Ioanna Goutziamani; Andreas Soloukides; Lakis Yioukas; Avraam Elia; Ioanna Zouvani; Polys Polycarpou; Alkis Pierides; Konstantinos Voskarides; Constantinos Deltas  Human Genetics  (presented and approved for publication in July 2014). 

28. Frequency of COL4A3/COL4A4 mutations amongst families segregating glomerular microscopic hematuria and evidence for activation of the unfolded protein response. Focal and segmental glomerulosclerosis is a frequent development during ageing. Papazachariou L, Demosthenous P, Pieri M, Papagregoriou G, Savva I, Stavrou C, Zavros M, Athanasiou Y, Ioannou K, Patsias C, Panagides A, Potamitis P, Demetriou K, Prikis M, Hadjigavriel M, Kkolou M, Loukaidou P, Pastelli A, Michael A, Lazarou A, Arsali M, Damianou L, Goutziamani I, Soloukides A, Yioukas L, Elia A, Zouvani I, Polycarpou P, Pierides A, Voskarides K, Deltas C  PLoS One 2014 Dec 16;9(12):e115015. doi: 10.1371/journal.pone. 0115015. e Collection 2014. 

29. Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients Christoforos D Giannaki, Michael Hadjigavriel, Akis Lazarou, Aristos Michael, Loukas Damianou, Efthimios Atmatzidis, Ioannis Stefanidis, Georgios M Hadjigeorgiou, Giorgos K Sakkas, Marios Pantzaris World J Nephrol. Sep 6, 2017; 6(5): 236-242 

30. COL4A5 and LAMA5 variants co-inherited in familial hematuria: digenic inheritance or genetic modifier effect? Voskarides K, Papagregoriou G, Hadjipanagi D, Petrou I, Savva I, Elia A, Athanasiou Y, Pastelli A, Kkolou M, Hadjigavriel M, Stavrou C, Pierides A, Deltas C (2017) BMC Nephrol in Press. 

31. Investigation of Alport and Alport-like cases through NGS technology reveals digenic and contigouous gene syndrome inheritance Papagregoriou G, Hadjipanagi D, Voskarides K, Stylianou K, Athanasiou Y, Zavros M, Arsali M, Michael A, Papachristou F, Printza N, Frankou e, Gkinis V, Kasimatis E, Zoumbarides, N, Georgiou I, Giatras I, Lilova M, Tzanakis I, Papadaki A, Kkolou M, Loukaidou P, Pastelli A, Paliouras C, Alivanis A, Vegoulas G, Pierides A, Dafnis E, Hadjigavriel M, Deltas C.  
 
32. Evidence for the contribution of a LAMA5 variant in familial microscopic hematuria Voskarides K, Papagregoriou G, Hadjipanagi D, Petrou I, Savva I, Elia A, Athanasiou Y, Pastelli A, Kkolou M, Hadjigavriel M, Stavrou C, Pierides A, Deltas C. 

33. COL4A5 and LAMA5 variants co-inherited in familial hematuria: digenic inheritance or genetic modifier effect? Voskarides K, Papagregoriou G, Hadjipanagi D, Petrou I, Savva I, Elia A, Athanasiou Y, Pastelli A, Kkolou M, Hadjigavriel M, Stavrou C, Pierides A, Deltas C (2017) BMC Nephrol In Press. 


MEMBERSHIPS
  • EUROPEAN SOCIETY OF ORGAN TRANSPLANTATION (ESOT) 
  • MIDDLE EAST SOCIETY OF ORGAN TRANSPLANTATION (MESOT) 
  • EUROPEAN DIALYSIS TRANSPLANT ASSOCIATION (EDTA) 
  • EUROPEAN SOCIETY OF ARTIFICIAL ORGANS (ESAO) 
  • GREEK SOCIETY OF NEPHROLOGY (ENE) 
  • CYPRUS MEDICAL ASSOCIATION (CMA) 
  • ITALIAN SOCIETY OF NEPHROLOGY (SIN) 
  • CYPRUS SOCIETY OF NEPHROLOGY (NEK) / (VICE PRESIDENT 2012-2014) 
  • MOLECULAR MEDICINE RESEARCH CENTER - UNIVERSITY OF CYPRUS (ASSOC. MEMBER) 
  • EUROPEAN COUNCIL /  EUROPEAN COMMITTEE ON ORGAN TRANSPLANTATION (EDQM), (NATIONAL DELEGATE OF CYPRUS 2014-2017)
  • EUROPEAN UNIVERSITY CYPRUS (EUC) (ADVISORY BOARD 2017-CURRENT) 
  • CYPRUS INSTITUTE OF NEUROLOGY AND GENETICS (CING) (BOARD OF DIRECTORS 2017-CURRENT)

SOCIAL MEMBERSHIPS
  • SLOW FOOD CYPRUS (FOUNDING MEMBER AND NATIONAL REPRESENTATIVE) 

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