Dr Neophytos A. Zambas

Dr Neophytos A. Zambas

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Dr Neophytos A. Zambas

Dr Neophytos A. Zambas MD, PhD.

Vascular Surgeon


Dr. Zambas graduated from the Medical School of the Aristotle University of Thessaloniki in 2002. The same year enter the Specialty of Vascular Surgery at Hippokration Hospital of Thessaloniki where he trained in General Surgery up to 2005.

From October 2005 to June 2008 he trained in UK at Ealing and Hammersmith Hospitals (Imperial NHS Trust). At these hospitals had the opportunity to deal with gene therapy for peripheral arterial disease, to be trained in foam sclerotherapy and laser treatment for varicose veins the open and the endovascular surgery in all the aspects of the specialty of vascular surgery. In 2008 he returned to Thessaloniki to finish the Specialty at Hippokration Hospital. In March 2010 he defended successfully with distinction his PhD Thesis. 

On October 2010 passed successfully the final exams of the Specialty of the Vascular Surgery. From November 2010 to September 2011 he work in private practice and trained in endovascular surgery in Blue Cross (Kyanos Stavros) Euromedical Cardiovascular Surgery center in Thessaloniki.

He is a member of the General Medical Council of the United Kingdom, member of the European Society of Vascular and Endovascular Surgery member of the Royal Society of Medicine, UK, and member of Thessaloniki Medical Association. He is also a member and elected treasurer of the Cyprus Society of Vascular and Endovascular Surgery.


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Vascular Surgery

The specialty of vascular surgery is one of the new specialties. In most of the countries began to be independent specialty the decade of 1990. Vascular Surgery deals with the pathology and treatment of the arteries, veins and lymphatic vessels of the human body except the vessels of the brain and the heart. The development of the specialty was huge the last two decades with the new endovascular procedures and methods to win over the classic cold standards procedures. Thus the new endovascular procedures in most of the cases and with the right indications become the cold standard. Dr Neophytos Zambas has been trained in the new methods like the endovascular repair of abdominal aneurysms, laser ablation of the great saphenous vein and foam sclerotherapy for varicose veins. Peripheral artery balloon angioplasty and stenting for peripheral arterial disease, percutaneous balloon angioplasty and stenting for carotid artery disease and diabetic foot are Dr Zambas special interests. For example symptoms that indicate that you may suffer from peripheral vascular arterial disease is intermittent pain on walking and exercise (intermittent Claudication).Night cramps and, swelling on the legs, are symptoms of varicose veins. Amaurosis fugax, speech problems and numbness of the arm or the leg could be symptoms of a stroke. Redness and pain on your legs could be signs of superficial thrombophlevitis especially if you have varicose veins. Long standing unhealed leg ulcers may be the result of vein incompetence. A sudden pain on the abdomen and the lower back can be the result of an abdominal aneurysm. In these cases you need a proper assessment by a vascular surgeon. High risk patients for vascular disease are diabetics, people who suffered a stroke or have numbness on the hand or on the foot, people with high blood pressure and hypercholesterolemia and heavy smokers.

Vascular Consulation

For diagnostic purposes the following examinations are performed to the doctors medical practice: Doppler of the legs arteries (Ankle Brachial Pressure Index – ABPI) Color Ultrasound Duplex Scan Carotid Arteries Abdominal Aorta and Splachnic Arteries (renal, superior mesenteric) Iliac vessels Arteries and Veins of the lower limbs Arteries and Veins of the Upper Limbs Further examinations would be requested by the doctor when there is indication after the primary consultation. These are the following: Computer Tomography Angiography (CTA) Magnetic Resonance Angiography (MRA) Digital Subtraction Angiography (DSA).

Vascular Conditions

VEINS Varicose Veins Spider Veins Vein ulcers Vein Thrombosis Upper Limb Legs Superficial Vein Thrombosis Deep Vein Thrombosis Venous Malformations (Klippel–Trénaunay–Weber syndrome) ARTERIAL ARTERIAL ANEURYSMS Abdominal Aortic Aneurysm Thoracic Aortic Aneurysm Iliac Artery Aneurysm Femoral Artery Aneurysm Popliteal Artery Aneurysm Renal artery aneurysm Mesenteric Artery Aneurysm Carotid Artery Aneurysm ARTERIAL DISEASES Carotid Artery Stenosis Rupture Arteries Arterial occlusive disease of the legs Arterial dissection Diabetic Foot Mesenteric Ischemia LYMPHATIC SYSTEM Lower limb lymphedema Upper Limb lymphedema OTHER DISEASES Reynauds’ Syndrome/Disease Burger Disease Thoracic Outlet Syndrome Temporal Arteritis.


LASER TREATMENT: Laser treatment has been established as a method of choice for the treatment of varicose veins. Laser offers very good results on the treatment of varicose veins and the benefits compare with the classic saphenectomy with stripping is less pain postoperatively, earlier mobilization, less complications and better aesthetic result as there is no scar on the groin and no stitches. The procedure is offered as a daily procedure and you can go home the same day. The doctor is using the biolitec laser with radial function for better results. Carotid artery stenting: (SEE THE VIDEO IN "VIDEOS" SECTION).


Your medical insurance will cover or not your medical expenses according to your contract. If you need an operation all the medical insurance companies will cover you. On this case you have two options. The first is for you to pay the operation and the doctor yourself and afterwards you will claim the amount from your medical insurance. The second option is to pay nothing and the hospital will be paid directly from your insurance. You just need to present your medical insurance card or the number of your contract to the hospital and the hospital will do the rest for you. All the international and domestic medical insurance companies collaborate with the private hospitals in Cyprus. Regarding the consultation and the image examinations like the ultrasound or the computer tomography (CT scan) you pay the cost yourself. If your contract covers these expenses you will be refunded the money by your insurance. In the last case you need to present the report and the invoice of the examination. If you need further information please contact us. PATIENTS FROM ABROAD: Cyprus is a small sunshining country located between Europe, Assia and Africa in the East Mediterannean Sea. Cyprus is a full member of the European Union since 2004 and menber of the Euroze since 2008. The doctor offer his services to private hospitals with the state of the art facilities in Nicosia, Limassol and Paphos. The good climate contitions all over the year, the easy transportation to the country, the hospitality of the people, the facilities like hotels, airports and hospitals makes the country one of the favorite tourist destinations all over the world. There is no language barrier as most of the people speak the english language and in some cities people speak russian and other languages. The doctor offers his services in collaborate private hospitals in three cities, Limassol, Nicosia and Paphos. If you want to book an appointment please contact us. We can arrange everything for you through collaborate agencies from all over the world. For more information about Cyprus visit the websites: www.visitcyprus.org.cy and www.europa.eu

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Personal Information


Personal Information

+357 25 35 2004

Location Information

Postal Address:
Postal Code:
City Name:

Second Location

2nd Postal Ad.
Ygia Polyclinic Private Hospital, 21, Nafpliou street
2nd Town:
2nd Postal C.
2nd City:

Third Location

3rd Postal Ad.
Evangelismos Private Hospital, 87 Vasileos Constantinou XIII,
3rd Town:
3rd City:
3rd Postal C.


Medical School of the Aristotle University of Thessaloniki
Other Universities:
Hippokration Hospital of Thessalonik


Practice Experience:
Trained in UK at Ealing & Hammersmith Hospitals (Imperial NHS Trust) (Oct 2005 - Jun 2008)
  • Gene therapy for peripheral arterial disease
  • Foam sclerotherapy & laser treatment for varicose veins
  • Open and endovascular surgery in all the aspects of the specialty of vascular surgery
Hippokration Hospital Thessaloniki
  • Defended successfully with distinction his PhD Thesis (Mar 2010)
  • Successfully passed the final exams of the Specialty of the Vascular Surgery (Oct 2010)
Blue Cross (Kyanos Stavros), Euromedical Cardiovascular Surgery center, Thessaloniki
  • Private practice and trained in endovascular surgery (Nov 2010 - Sept 2011)
Clinical / Academic Interests:

Participation in two international multicenter studies:

  1. As Co – Investigator in the ENGAGE Registry. This is a multicenter prospective registry of the ENDURANT Stent graft (Medtronic) for endovascular treatment of abdominal aneurysm. A
  2. s Co – Investigator to the “WALK” study for patients with intermittent Claudication. This was a study investigated the gene therapy treatment in patients with intermittent Claudication.  He participated under Mr George Geroulakos at Ealing και Hammersmith Hospital (Imperial Trust). The title of the study was  “A Phase 2, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter, Dose – Selection Study of Ad2/Hypoxia Inducible Factor HIF – 1alpha/VP16 in Patients with Intermittent Claudication “ 
  3. As a PhD candidate he investigated in an experimental protocol the protective effect of ATIII in lungs and heart in the ischemia reperfusion syndrome of the lower limb. A part of the results published in Annals of Vascular Surgery journal in May 2012.

Doctor Specialties

Special Expertise:
  • Laser for Varicose Veins
  • Endovascular Aneurysm Repair (EVAR)
  • Peripheral Arterial Disease (PAD)
  • Carotid endarterectomy (CEA)
  • Carotid Stenting (CAS)
  • Diabetic Foot
  • Spider Veins
  • Vein Thrombosis
  • Arterial Thrombosis


Hospital Type:
Hospital Address:
POLYCLINIC YGEIA (21, Nafpliou str., 3305) Tel: 25884600
Hospital Specialty:

Other Info

Publications & Presentations:
  • General Medical Council of the United Kingdom
  • European Society of Vascular and Endovascular Surgery
  • Royal Society of Medicine, UK 
  • Thessaloniki Medical Association
  • Member and elected treasurer of the Cyprus Society of Vascular and Endovascular Surgery.

  • Papazoglou K, Mallios A, Rafati F, Zambas N, Karkos C. Endovascular Treatment of Ruptured Abdominal Aortic Aneurysms With the Endurant Device. Ann Vasc Surg. 2012 Sep 12 [Epub ahead of print] 
  • Papazoglou KO, Sfyroeras GS, Zambas N, Konstantinidis K, Kakkos SK, Mitka M. : Midterm outcomes of endovascular aneurysm repair with selective internal iliac artery coverage without coil embolization, J Vasc. Surg. 2012 May 
  • Zambas NA, Karkos CD, Kambaroudis AG, Karamanos DG, Spyridis CT, Gerassimidis TS. Protective Effect of Antithrombin III Against Lung and Myocardial Injury in Lower-Limb Ischemia-Reperfusion Syndrome. Ann Vasc Surg. 2012 May;26(4):566-70. 
  • Kalodiki E; Azzam M; Lattimer CR; Shawish E; Zambas N; Geroulakos G. (2011). Randomized controlled trial of ultrasound guided foam sclerotherapy combined with sapheno-femoral ligation compared to surgical treatment of varicose veins: Five-year results (abst). Journal of Vascular Surgery. 53:259-260. 
  • Karkos CD, Karamanos DG, Papadimitriou DN, Demiropoulos F, Zambas N and Gerassimidis TS: An unusual complication of a “blind” femoral embolectomy. Annals of vascular surgery 24(6):824.e15-7, 2010 Aug. 
  • Karkos CD, Karamanos DG, Papazoglou KO, Papadimitriou DN, Zambas N, Gerogiannis IN, Gerassimidis TS:Axillary artery transection after recurrent anterior shoulder dislocation. Am J Emerg Med. 2010 Jan;28(1):119.e5-7. 
  • G. Geroulakos, N Zambas “Debranching of the aorta produces thrombosis of the false lumen in selected cases of chronic type A aortic dissection” International Angiology 2009, Feb; 28 (1): 79-81 
  • N. Zambas, G Geroulakos, N Mazarakis, “Gene Therapy in Claudication”, Vascular and Endovascular Surgery Highlights 2007-08 
  • A. Ntinas, N. Zambas, S Al Mogrambi, P. Petras, E. Halvatzoulis, G. Frangandreas, D.Tsandilas, T. Gerasimidis,‘’Postoperative follow up of patients with colorectal cancer (A combined evaluation of CT scan, colonoscopy and tumor makers)’’. Tech Coloproctol. 2004 Nov; 8 Suppl 1:s190-2. 
  • D. Tsandilas, A. Ntinas, P. Petras, N. Zambas, S. A1 Mogrambi, G. Frangandreas, C. Spyridis, T. Gerasimidis‘’Metachronous colorectal adenocarcinomas’’., Tech Coloproctol. 2004 Nov; 8 Suppl 1:s202-4.



Vascular surgery training in Europe and United States, 12ο Hellenic Congress of Angiology and Vascular Surgery, January 2010, Athens (Invited speaker) 

Experience of a decade of endovascular treatment of aortic aneurysms with the AneuRx stent graft.  Papazoglou K, Zambas N, Karkos C, Karamanos D, Demiropoulos Ph, Papadimitriou D, Gerasimides Th. 12ο Hellenic Congress of Angiology and Vascular Surgery, January 2010, Athens 

Protective effect of Antithrombin III against lung and myocardial injury in lower limb ischemia reperfusion syndrome. Zambas N, Karkos C, Karamanos D, Kambaroudis A, Papazoglou K, Iliadis S, Koliakou K, Spyrides C, Papageorgiou G, Gerassimides 12ο Hellenic Congress of Angiology and Vascular Surgery, January 2010, Athens 

Axillary artery transection following anterior shoulder dislocation: revascularization using open surgical, endovascular or hybrid techniques. CD Karkos, DG Karamanos, KO Papazoglou, IN Gerogiannis, DN Papadimitriou, FP Demiropoulos, NA Zambas, A. Kamparoudis, TS Gerasimidis. AVEM 2009, 12-14 March, Thessaloniki 

Protective effect of Antithrombin III against lung and myocardial injury in lower limb ischemia reperfusion syndrome. Zambas N, Karamanos D, Karkos C, Kambaroudis A, Iliadis S, Papageorgiou G, Bassagiannis I, Spyrides C Gerassimides 24th Northen Greece medical Congress , 26-28 March 2009, Thessaloniki. 

Infrapopliteal angioplasty using the Kissing Balloon technique in the management of ischemic diabetic foot ,Gerassimidis S Th, Karamanos G.D, Karkos CD, Papadimitriou N.D , Demiropoulos P. F , Zambas N, Diplaris K, Vougiouklis N, 4th World Congress on Quality in Medical Practice, October 2-4, 2008, Thessaloniki 

The impact of subintimal angioplasty on the management of patients with Superficial Femoral Artery (SFA) occlusive disease , Gerassimidis S Th, Karkos CD, Karamanos G.D, Papazoglou O. K, Zambas N, Demiropoulos P. F, Papadimitriou N.D, Kamparoudis G.A, Pezikoglou I., 4th World Congress on Quality in Medical Practice, October 2-4, 2008, Thessaloniki 

Incidence and significance of haemodynamic instability after carotid angioplasty and stenting for stroke prophylaxis, Gerassimidis S. Th, Mallos A., Karkos D Ch, Karamanos G.D, Papazoglou O.K, Demiropoulos F, Papadimitriou N.D, Malkotsis P.D, Zambas N, Liasidis Ch *, Fileli A**,  Pezikoglou I** , 4th World Congress on Quality in Medical Practice, October 2-4, 2008, Thessaloniki 

‘’Endovascular Aneurysm Repair (EVAR) Ealing Experience’’ Grand Round, Ealing Hospital NHS Trust, 28 February 2008 
Effect of Cilostazol in patients with Peripheral Arterial Disease ‘’Innovations for the management of peripheral vascular disease in West London’’ 12 Dec 2007 

‘’A complication of Type A aortic dissection’’, Grand Round, Ealing Hospital NHS, 13 September 2007 
Poster: The WALK study, Gene Therapy Research Day, Imperial College of London, September 25th , 2006 

‘’Injuries of Peripheral Arteries’’, 9th Hellenic Congress of Vascular Surgery, 23-25 January 2004, Athens, Greece. 

«The importance of tumor markers in the post operative follows up in patients with colorectal cancer. » Tsantilas D, Zambas N, Fragkandreas G, Kamparoudis A, Spyrides C, Ntinas A, Tsantilas V, Filleli A. 6th Greek – Cyprus Surgical Meeting, 24-26 October, Nicosia, Cyprus 

«Traumatic Thoracid Injuries», Zambas N, Georgolios A, Spanos P, Vouxaras C, 1st Scientific Congress of Aristorele University of Thessalonica Medical School, February 2002, Thessalonica, Greece 

«Stress» Zambas N, Amirides E, Papaioannou S, Beshari N, Boutzioukas S, 5th Greek Medical StudentsAsssociation Union, April 1999, Alexandroupolis, Greece

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