Respiratory distress syndrome, Neonatal
Introduction
Neonatal respiratory distress syndrome (NRDS) happens when a newborn baby's lungs aren't fully developed and they can provide enough oxygen. It usually affects premature babies.
NRDS is also known as:
hyaline membrane disease
infant respiratory distress syndrome
newborn respiratory distress syndrome
surfactant deficiency lung disease (SDLD)
Despite having a similar name, acute respiratory distress syndrome (ARDS) isn't related. ARDS is caused by a serious underlying health condition and can affect people of any age.
Why it happens
NRDS most often occurs when there isn't enough surfactant in the lungs. This substance, made up of proteins and fats, helps keep the lungs inflated and prevents parts of the lung called air sacs collapsing.
A baby normally begins producing surfactant sometime between weeks 24 and 28 of pregnancy. Most babies produce enough surfactant to breathe normally by week 34. If your baby is born prematurely, they may not have enough surfactant in their lungs.
Occasionally, NRDS occurs in babies that aren't born prematurely. This is usually due to other risk factors, such as:
the mother having diabetes
the baby being underweight
poor lung development, which can be caused by a variety of illnesses
Problems with the genes can play a role in lung development, but this is very rare.
It's estimated that half of all babies born before 28 weeks of pregnancy will develop NRDS. However, this has reduced in recent years, as steroid injections can be given to mothers at risk of NRDS during premature labour.
Signs and symptoms
The signs of NRDS are often noticeable immediately after birth and get worse over the following few days. They can include:
blue-coloured lips, fingers and toes
rapid, shallow breathing
flaring nostrils
a grunting sound when breathing
As premature babies are usually born in hospital, most babies with NRDS are already in hospital when they develop these problems and receive treatment (see below).
If you give birth outside hospital and notice the above symptoms in your child, call 999 immediately and ask for an ambulance.
Diagnosing NRDS
A number of tests can be used to look for the signs of NRDS and rule out other possible causes.
These tests may include:
a physical examination
blood tests – to measure the amount of oxygen in the blood and check for an infection
a pulse oximetry test – to measure how much oxygen is being absorbed in the blood, using a sensor attached to the fingertip, ear or toe
a chest X-ray – to look for the distinctive cloudy appearance of NRDS
Treating NRDS
Most babies with NRDS need breathing help with extra oxygen and possibly some form of ventilator support. Babies needing ventilation can often be treated with a medication directly into the lungs called artificial surfactant, which helps to restore normal lung function.
Some cases can be prevented or at least made less severe by treating the mother with a medication called betamethasone before birth.
Complications
In the majority of cases, NRDS can be successfully treated and deaths directly linked to NRDS are rare in the UK.
However, in more severe cases, there's a risk of further problems. These can include scarring to the lungs, leading to longer-term breathing problems. There's also a risk of brain damage, which may result in problems such as learning difficulties.
Introduction
Neonatal respiratory distress syndrome (NRDS) happens when a newborn baby's lungs aren't fully developed and they can provide enough oxygen. It usually affects premature babies.
NRDS is also known as:
hyaline membrane disease
infant respiratory distress syndrome
newborn respiratory distress syndrome
surfactant deficiency lung disease (SDLD)
Despite having a similar name, acute respiratory distress syndrome (ARDS) isn't related. ARDS is caused by a serious underlying health condition and can affect people of any age.
Why it happens
NRDS most often occurs when there isn't enough surfactant in the lungs. This substance, made up of proteins and fats, helps keep the lungs inflated and prevents parts of the lung called air sacs collapsing.
A baby normally begins producing surfactant sometime between weeks 24 and 28 of pregnancy. Most babies produce enough surfactant to breathe normally by week 34. If your baby is born prematurely, they may not have enough surfactant in their lungs.
Occasionally, NRDS occurs in babies that aren't born prematurely. This is usually due to other risk factors, such as:
the mother having diabetes
the baby being underweight
poor lung development, which can be caused by a variety of illnesses
Problems with the genes can play a role in lung development, but this is very rare.
It's estimated that half of all babies born before 28 weeks of pregnancy will develop NRDS. However, this has reduced in recent years, as steroid injections can be given to mothers at risk of NRDS during premature labour.
Signs and symptoms
The signs of NRDS are often noticeable immediately after birth and get worse over the following few days. They can include:
blue-coloured lips, fingers and toes
rapid, shallow breathing
flaring nostrils
a grunting sound when breathing
As premature babies are usually born in hospital, most babies with NRDS are already in hospital when they develop these problems and receive treatment (see below).
If you give birth outside hospital and notice the above symptoms in your child, call 999 immediately and ask for an ambulance.
Diagnosing NRDS
A number of tests can be used to look for the signs of NRDS and rule out other possible causes.
These tests may include:
a physical examination
blood tests – to measure the amount of oxygen in the blood and check for an infection
a pulse oximetry test – to measure how much oxygen is being absorbed in the blood, using a sensor attached to the fingertip, ear or toe
a chest X-ray – to look for the distinctive cloudy appearance of NRDS
Treating NRDS
Most babies with NRDS need breathing help with extra oxygen and possibly some form of ventilator support. Babies needing ventilation can often be treated with a medication directly into the lungs called artificial surfactant, which helps to restore normal lung function.
Some cases can be prevented or at least made less severe by treating the mother with a medication called betamethasone before birth.
Complications
In the majority of cases, NRDS can be successfully treated and deaths directly linked to NRDS are rare in the UK.
However, in more severe cases, there's a risk of further problems. These can include scarring to the lungs, leading to longer-term breathing problems. There's also a risk of brain damage, which may result in problems such as learning difficulties.
Respiratory distress syndrome,Neonatal